Natural Cell-Mediated Cytotoxicity in Cutaneous T-Cell Lymphomas
نویسندگان
چکیده
منابع مشابه
Primary cutaneous T-cell lymphomas.
Primary cutaneous T-cell lymphomas (CTCLs) encompass a clinically and biologically heterogeneous group of non-Hodgkin lymphomas (NHLs) defined by clonal proliferation of skin-homing malignant T lymphocytes and natural killer cells. They account for up to 75% to 80% of all cutaneous lymphomas. The current WHO-EORTC classification of cutaneous lymphomas with primary cutaneous manifestations lists...
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Sera from patients with cutaneous T cell lymphoma and leukemia were screened for the presence of natural antibody to the human T cell lymphoma (leukemia) virus, HTLVCR, using a solid-phase radioimmunoassay. Sera from two patients, including patient CR, from whose cultured T lymphoblastic cell line (HUT102), the retrovirus HTLVCR was isolated, reacted specifically with proteins of HTLVCR. Serum ...
متن کامل[Eczema herpeticum in cutaneous T-cell lymphomas].
1. Bardach H. Perforating lichen nitidus. J Cutan Pathol. 1981;8:111-6. 232-6. 2. Banse-Kupin L, Morales A, Kleinsmith DA. Perforating lichen nitidus. J Am Acad Dermatol. 1983;9:452-6. 3. Itami A, Ando I, Kukita A. Perforating lichen nitidus. Int J Dermatol. 1994;33:382-4. 4. Yoon TY, Kim JW, Kim MK. Two cases of perforating lichen nitidus. J Dermatol. 2006;33:278-80. 5. Rudd ME, Ha T, Schofiel...
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Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of primary cutaneous T-cell lymphoproliferative processes, mainly composed of mycosis fungoides and Sézary syndrome, the aggressive forms of which lack an effective treatment. The molecular pathogenesis of CTCL is largely unknown, although neoplastic cells show increased signaling from T-cell receptors (TCRs). DNAs from 11 patients with ...
متن کاملGenotypic analysis of cutaneous T-cell lymphomas.
The gene encoding the beta-chain of the T-cell antigen receptor (TCR) has been analyzed for evidence of rearrangement in skin, blood, and lymph node specimens from 23 cases of known or suspected cutaneous T-cell lymphoma (CTCL). Two cutaneous large cell lymphomas, 4 cases of Sézary syndrome, and 5 cases of advanced (tumor) stages of mycosis fungoides showed clonal rearrangement of the TCR beta-...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1983
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12543616